
Bigger vehicles including electric can cause multiple harms, yet resistance to rise of SUVs and trucks has had mixed support
On a brisk winter’s evening in Europe’s automotive heartland, a cyclist who had pushed for safer streets went out on his bike for a final time. Andreas Mandalka had documented dangerous driving and shoddy cycling infrastructure for years, measuring the margins at which cars zipped past him and posting videos of blatant violations. While quick to remind readers that only a small proportion of drivers behaved badly, the 44-year-old blogger in Baden-Württemberg, Germany, had grown frustrated with authorities for failing to act. He felt they viewed him as a nuisance.
As he cycled down a straight stretch of renovated road that runs parallel to a forest path he had flagged for poor quality, lights bright on his bike and helmet firm on his head, he was fatally struck from behind by a car.
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Debate continues to rage over whether a strange carcass found in 1937 was a new species or a basking shark. Either way, the case reveals how little is known about what lies beneath the waves
Its head resembled a dog’s, its downturned nose a camel’s, and at the end of its reptilian body was the tail of horse. Witnesses say it was covered in a thin white film. When the remains of a strange creature were pulled from the stomach of a sperm whale, most of those present agreed: it was a sea monster – or at least something unknown living in the depths off Canada’s west coast.
Crews at the whaling station in the archipelago of Haida Gwaii assembled a platform of wooden boxes and laid out the 3-metre (10ft) carcass, using a white sheet to display the curiosity that had baffled veteran whalers.
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Firm benefits from conflict to rake in $6.9bn as higher energy prices turbocharge profits
Shell has reported better than expected profits of $6.9bn (£5bn) after its oil traders reaped the benefits of soaring energy prices during the war in Iran, angering climate campaigners.
Europe’s biggest oil and gas company posted a 115% jump in first-quarter profits from the $3.2bn reported in the last three months of 2025.
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As Reform vows to block solar and windfarms, energy leaders say renewables offer most secure future, insulating UK from hostile forces
• May elections: What’s at stake across England, Wales and Scotland?
The defining issue of Thursday’s local elections, feedback from doorsteps suggests, will be the UK’s soaring cost of living. But voters should be told about the links between inflation and the effects of fossil fuels and the climate crisis – or the remedies they choose – may make the situation worse, green campaigners have warned.
Ami McCarthy, the head of politics at Greenpeace UK, said: “With people’s bills and prices soaring from yet another fossil fuel crisis, these local elections have a global context – driven by the Iran war.
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Approval for exploration in 70 new areas prompts fierce backlash from fossil fuel opponents
The Norwegian government has been heavily criticised for approving plans to reopen three North Sea gasfields nearly three decades after they were closed to help fill the gap in energy supplies created by the Middle East war.
Amid sharp price rises in oil and gas since the US and Israel’s attack on Iran in February, Oslo has also given its approval for oil and gas companies to explore in 70 new locations in the North Sea, Barents Sea and Norwegian Sea.
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Julie, once a circus elephant, and Kariba, from a Belgian zoo, are to be moved to a former ranch in Portugal
Europe’s first large-scale elephant sanctuary, which is opening to offer a more natural environment for some of the 600 animals still held in captivity across the continent, is to receive its first arrivals.
Julie, Portugal’s last circus elephant, will be moved next month to the animal charity Pangea’s multimillion pound sanctuary in the Alentejo, 200km (124 miles) east of Lisbon, close to the border with Spain.
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Powerful property and farming firm Grosvenor Group says knock-on effect of Iran war could arrive next year
Fertiliser shortages caused by the Iran war have driven up costs for UK farmers by up to 70% and will have a “dramatic” impact on food prices globally next year, according to one of Britain’s most powerful property and farming companies.
Mark Preston, executive trustee of the 349-year-old Grosvenor Group, controlled by the Duke of Westminster, said fertiliser “was already quite expensive” before the 50% to 70% surge in prices since the start of the Iran war in late February.
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Powerful radar system is providing new data on city’s subsidence, which experts hope will draw more attention to it
Walking into Mexico City’s sprawling central Zócalo is a dizzying experience. At one end of the plaza, the capital’s cathedral, with its soaring spires, slumps in one direction. An attached church, known as the Metropolitan Sanctuary, tilts in the other. The nearby National Palace also seems off-kilter.
The teetering of many of the capital’s historic buildings is the most visible sign of a phenomenon that has been ongoing for more than a century: Mexico City is sinking at an alarming rate.
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To celebrate Sir David Attenborough’s centenary, Madeleine Finlay catches up with natural history writer Patrick Barkham, who has met the celebrated presenter. They explore how the natural world has changed in the century that Attenborough has been on Earth, and how his programming has reflected his growing commitment to highlighting the devastating impacts of the climate crisis on nature and biodiversity
Clips: BBC, PBS
Support the Guardian: theguardian.com/sciencepod
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The author has become acutely aware of how the climate crisis is affecting women – and, in her new book, she argues that it’s time for mainstream western feminists to join the dots
Natasha Walter is halfway through explaining how she came to be politically radicalised when a young woman approaches the cafe table. We two middle-aged women look like “the most trustworthy people here,” she says, so could we watch her baby while she grabs a coffee? Like the solid citizen she is, Walter doesn’t take her eyes off the pushchair parked by the cafe steps for the next five minutes, though all we can see of the occupant is a tiny swinging foot. Sorry, where were we? Ah yes, the groundbreaking feminist writer who famously argued in her 1998 book The New Feminism that Margaret Thatcher had broken down barriers for women was explaining why she no longer really believes it’s possible to be rightwing and a feminist, as Theresa May or Amber Rudd insist they are.
“I can’t support just any woman getting into power, because I think a system that leaves too many women in the shadows – that condemns too many women to poverty or worse – is not a feminist system, and I don’t think you can call yourself a feminist if you’re going to prop up that system,” she says, eyes still glued to the baby for whom we are briefly responsible. “It’s not my kind of feminism.” Her younger self, she admits, would have thought her too uncompromising. But something in her seems to have hardened, facing a world she sees as threatened by the rise of far-right authoritarianism on one hand and a climate emergency on the other. “In the past I always wanted to be a broad church, I always thought any woman can be a feminist, but now I really am feeling … maybe I’ve been radicalised.”
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Amiotrofična lateralna skleroza (ALS) je neurodegenerativna bolest koja uzrokuje progresivni gubitak motornih neurona, što u većini slučajeva dovodi do respiratornog zatajenja unutar tri do pet godina nakon dijagnoze. No, sada je nova studija utvrdila da je stanični selektivni sustav čišćenja proteina: autofagija posredovana šaperonima, značajno smanjen kod pacijenata, što ga čini potencijalnom terapijskom metom za usporavanje napredovanja bolesti.
Rezultati nove studije sugeriraju da su i vrlo niske i vrlo visoke vrijednosti otkucaja srca u mirovanju povezane s povećanim rizikom od moždanog udara. Smatra se, da rezultati ove studije osporavaju pretpostavku da su niži otkucaji srca uvijek znak dobre kardiovaskularne kondicije i da ne nose rizik.
Novo istraživanje pruža dokaze da se sindrom osjetljive kože (SSS) biološki razlikuje od rozaceje, pomažući razjasniti dugogodišnju raspravu u dermatologiji i potencijalno usmjeravajući ciljanije pristupe liječenju.
Desetljećima su se antimikrobni peptidi (AMP) i peptidi koji stvaraju amiloid proučavali u uglavnom odvojenim kontekstima. AMP-ovi su se prvenstveno smatrali urođenim imunološkim efektorima koji pomažu domaćinu u kontroli mikrobne invazije, dok je agregacija amiloida češće bila povezana s poremećajima poput Alzheimerove bolesti (Aβ), Parkinsonove bolesti (α-sinuklein), dijabetesa tipa 2 (hIAPP) i sistemske amiloidoze. Ipak, sve veći broj dokaza dovodi u pitanje ovo jasno odvajanje.
Sepsa, životno opasno stanje uzrokovano disreguliranim odgovorom domaćina na infekciju, ostaje glavni uzrok globalne smrtnosti. Srčana disfunkcija uzrokovana sepsom (SICD), poznata i kao septička kardiomiopatija, značajno pogoršava ishode pacijenata i nedostaju joj ciljane terapije. Iako su upala i metabolički poremećaji poznati kao uzroci, precizni molekularni mehanizmi koji pokreću SICD ostaju slabo shvaćeni, što ometa razvoj učinkovitih tretmana.
Konzumacija jaja povezana je s nižim rizikom od dijagnoze Alzheimerove bolesti za osobe starije od 65 godina, tvrdi nova studija. Naime, konzumacija jednog jajeta dnevno najmanje pet dana u tjednu smanjuje rizik od Alzheimerove bolesti do 27%.
Procjenjuje se da je 7% svih muškaraca pogođeno neplodnošću. Višestruke studije na životinjama pokazale su da izloženost trajnim kemikalijama iz okoliša u ranom životu može negativno utjecati na muško reproduktivno zdravlje, a sada studija na ljudima sugerira isto.
Prema rezultatima nove studije, izgleda da bakterija Akkermansia muciniphila igra značajnu ulogu u regulaciji imuniteta domaćina, održavanju integriteta crijeva i utjecaju na ishode bolesti kod zaraznih i ginekoloških stanja.
Nova tehnika predciljane radioimunoterapije (PRIT) pokazala se sigurnom i učinkovitom u iskorjenjivanju tumora iz predkliničkog modela raka debelog crijeva. Višestupanjski teranostički pristup isporučuje alfa-emitirajuće zračenje izravno tumorima, a istovremeno ograničava izloženost zdravim tkivima.
U novoj studiji znanstvenici su otkrili da narkolepsija s iznenadnim gubitkom mišićne snage, poznata kao katapleksija, uključuje degeneraciju neurona ne u jednom, već u dva područja mozga.