Herbicidi na bazi glifosata: znanstveni radovi

Dokazi iz stručne literature koliko su štetni herbicidi na bazi glifosata. 

Herbicid u polju na Otoku Hvaru Herbicid u polju na Otoku Hvaru Foto: Vivian Grisogono

DOKAZI KOJI UKAZUJU NA ŠTETNOST HERBICIDA NA BAZI GLIFOSATA

[Nažalost, stručna literatura je uglavnom na engleskom jeziku. Ako znate za stručne radove koji bi bili korisni u ovoj evidenciji, molimo Vas da njih pošaljete nama na adresi: Ova e-mail adresa je zaštićena od spambota. Potrebno je omogućiti JavaScript da je vidite..]

Većina citiranih znanstvenih radova iz ovog popisa je objavljena u recenziranim časopisima. Tamo gdje je to bilo moguće, postavljeni su internetski linkovi za članke. Skoro svi članci imaju brojne reference na prethodna znanstvena istraživanja. Budući da je došlo do određene kontroverze u vezi sigurnosti glifosata, tražena su još i strožija istraživanja, kao što su: Landrigan, P.J., Belpoggi, F. 2018. Potreba za samostalnim istraživanjem zdravstvenih učinaka herbicida na bazi glifosata. (The need for independent research on the health-effects of glyphosate-based herbicides.) Environmental Health 17:51. 17 references.

Kao odgovor na ovu potrebu, nezavisno financirani Institu Ramazzini pokrenuo je Globalnu Studiju Glifosata u 2016. godini, čiji je rezultat prvi članak u recenziranom časopisu - pilot studija iz 2018. godine, koja je pokazala štetne učinke glifosata kod prethodno prihvaćenih "sigurnih doza"..

Pregled problematika

Cox, C., 1995. Glyphosate Fact Sheets: Part 1: Toxicology. Journal of Pesticide Reform. 15 (3) Fall 1995. Northwest Coalition for Alternatives to Pesticides, Eugene, OR. 50 references. 

Ho, M-W., Sirinathsinghji, E., 2012. Why Glyphosate should be banned - a review of its hazards to health and the environment. Permaculture Research Institute. (Institute of Science in Society Special Report) 107 references

Earth Open Source, 2012. Roundup and Birth Defects (overview, with industry responses)

Mason, Rosemary, 2013. Glyphosate Destructor of Human Health and Biodiversity. GMO Evidence

Friends of the Earth, June 2013. Concerns about Glyphosate's Approval. Friends of the Earth Europe (www.foeeurope.com)

Jošt. M. 2014. Zabranimo uporabu herbicida na bazi glifosata. Portal hrvatskoga kulturnog vijeća. 3 reference

Robinson, C., 2014. The glyphosate toxicity studies you're not allowed to see. GMWatch

Vandenberg, L.N., Blumberg, B., Antoniou, M.N., Benbrook, C.M., Carroll, L., Colborn, T., Everett, L.G., hansen, M., Landrigan, P.J., Lanphear, B.P., Mesnage, R., vom Saal, F.S., Welshons, W.V., Myers, J.P. 2016. Is it time to reasses current safety standards for glyphosate-based herbicides? Journal of Epidemiology and Community Health, (BMJ Journals) 71 (6) 55 references

Myers, J.P., Antoniou, M.N., Blumberg, B., Carroll, L., Colborn, T., Everett, L.G., Hansen, M., Landrigan, P.J., Lanphear, B.P., Mesnage, R., Vandenberg, L.N., vom Saal, F.S., Wlshons, W.V., Benbrook, C.M. 2016. Concerns over use of glyphosate-based herbicides and risks associated with exposures: a consensus statement. Environmental Health 15: 19.  80 references

Clausing, P., Robinson, C., and Burtscher-Schaden, H. 2018. Pesticides and public health: An analysis of the regulatory approach to assessing the carcinogenicity of glyphosate in the European Union. Journal of Epidemiology and Community Health. 20 references

Torretta, V., Katsoyiannis, I.A., Viotti, P., Rada, E.C. 2018. Critical Review of the Effects of Glyphosate Exposure to the Environment and Humans through the Food Supply Chain. Sustainability, MDPI Basel, Switzerland.  This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). 67 references

Landrigan, P.J., Belpoggi, F. 2018. The need for independent research on the health effects of glyphosate-based herbicides. Environmental Health , 17:51. 17 references

Defrage, N., Spiroux de Vendomois, J., Séralini, G.E., 2018. Toxicity of formulants and heavy metals in glyphosate-based herbicides and other pesticides. Science Direct: Toxicology Reports. 5: 156-163. 71 references

van Bruggen, A.H.C., He, M.M., Shin, K., Mai, V., Jeong, K.C., Finckh, M.R., Morris, J.G.Jr. 2018. Environmental and health effects of the herbicide glyphosate. Science of the Total Environment, 616-617: 255-268. 167 references

Gillezeau, C., Lieberman-Cribbin, W., Taioli, E. 2020. Update on human exposure to glyphosate, with a complete review of exposure in children. Environmental Health, 19, article 115. Published 12 November 2020. 26 references

Krimsky, S. 2021. Can Glyphosate-Based Herbicides Contribute to Sustainable Agriculture?  Sustainability 13 (4) 2337. 105 references

da Silva, K.A., Beltrame Nikola, V., Tavares Dudas, R., Demetrio, W.C., dos Santos Maia, L., Cunha, L., Bartz, M.L.C., Brown, G.G., Pasini, A., Kille, P., Ferreira, N.G.C., Ribas de Oliveira, C.M., 2021. Pesticides in a case study on no-tillage farming systems and surrounding forest patches in Brazil. Nature, Scientific Reports 11, 9839 (published 10th May 2021). 110 references

Straw, E.A., Carpentier, E.N., Brown, M.J.F. 2021. Roundup causes high levels of mortality following contact exposure in bumble bees. Journakl of Applied Ecology 06.04.2021. 61 references

Klatyik, S., Simon, G., Olah, M., Mesnage, R., Antoniou, M.N., Zaller, J.G., Szekacs, A. 2023. Terretstrial ecotoxicity of glyphosate, its formulations, and co-formulants: evidence from 2010 to 2023. Environmental Sciences Europe. Open access, published 08.07.2023. 280 references

KOD LJUDI

Utjecaj na otpornost na antibiotike

Liu, Y-B., Long, M-X., Yin, Y-J., Si, M-R., Zhang, L., Lu, Z-Q., Wang, Y., Shen, X-H. 2013. Physiological roles of mycothiol in detoxification and tolerance to multiple poisonous chemicals in Corynebacterium glutamicum. Archives of Microbiology 195 (6) 419-429. 48 references 

Kurenbach, B., Gibson, P.S., Hill, A.M., Bitzer, A.S., Silby, M.W., Godsoe, W., Heinemann, J.A. 2017. Herbicide ingredients change Salmonella enterica sv. Typhimurium and Escherichia coli antibiotic responses. Microbiology, online 17 November 2017 doi: 10.1099/mic.0.000573 40 references

Van Bruggen, A.H.C., He, M.M., Shin, K., Mai, V., Jeong, K.C., Finckh, M.R., Morris, J.G.Jr. 2018. Environmental and health effects of the herbicide glyphosate. Science of the Total Environment, 616-617: 255-268. 167 references

Liao, H., Li X., Yang, Q., Bai,Y., Cui, P., Wen, C., Liu, C., Chen, Z., Tang, J., Che, J., Yu, Z., Geisen, S., Zhou, S., Friman, V-P., Zhu, Y-G. 2021. Herbicide Selection Promotes Antibiotic Resistance in Soil Microbiomes. Molecular Biology and Evolution, 38 (6) 2337-2350. 75 references

van Bruggen, A.H.C., Finckh, M.R., He, M., Ritsema, C.J., Harkes, P., Knuth, D., Geissen, V. 2021. Indirect Effects of the Herbicide Glyphosate on Plant, Animal and Human Health Through its Effects on Microbial Communities. Frontiers in Environmental Science, Toxicology, Pollution and the Environment. published 18th October 2021. 250 references

Rizici rakova

De Roos, A.J., Blair, A., Rusiecki, J.A., Hoppin, J.A., Svec, M., Dosemeci, M., Sandler, D.P., Alavanja, M.C., 2005. Cancer Incidence among Glyphosate-Exposed Pesticide Applicators in the Agricultural Health study. Environmental Health Perspectives 113 (1) 49-54. 56 references

Eriksson, M., Hardell, L., Carlberg, M., Akerman, M., 2008. Pesticide exposure as risk factor for non-Hodgkin lymphoma including histopathological subgroup analysis. International Journal of Cancer 123: 1657-1663. 41 references

Samsel, Anthony & Seneff, Stephanie 2013. Glyphosate, pathways to Modern Diseases II: Celiac Sprue and Gluten Intolerance. Interdisciplinary Toxicology 6 (4) 159-184. 271 references

Thongprakalsang, S., Thiantanawat, A., Rangkadilok N., Suriyo, T., Satayavivad, J., 2013. Glyphosate induces human breast cancer cells growth via oestrogen receptors. Food & Chemical Toxicology 59: 129-136

Alavanja, M.C.R., Ross, M.K., Bonner, M.R., 2013. Increased Cancer Burden Among Pesticide Applicators and Others Due to Pesticide Exposure. CA: A Cancer Journal for Clinicians 63 (2): 120-142. 186 references

Séralini, G-E, Clair, E., Mesnage, R., Grass, S., Defarge, N., Malatesta, M., Hannequin, D., Spirouz de Vendômois, J., 2014. Republished study: long-term toxicity of a Roundup herbicide and Roundup-tolerant genetically modified maize.  Environmental Sciences Europe. 75 references.

Ho, M.W., 2014. Glyphosate and Cancer. Institute of Science in Society Report 26.3.2014. 34 references

Schinasi, L., Leon, M.E., 2014. Non-Hodgkin Lymphoma and Occupational Exposure to Agricultural Pesticide Chemical Groups and Active Ingredients: A Systematic Review and Meta-Analysis. International Journal of Environmental Research and Public Health 11 (4): 4449-4527. 77 references

International Agency for Research into Cancer, 2015. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. Vol.112 (2015) Some Organophosphate Insecticides and Herbicides. GlyphosateAuthors: Guyton, K.Z., Loomis, D., Grosse, Y., Ghissassi, F. E., Benbrahim-Tallaa, L., Guha, N., Scoccianti, C., Mattock, H., Straif, K.  on behalf of the International Agency for Research on Cancer Monograph Working Group, IARC, Lyon, France. Summary published in the Lancet Oncology, Vol. 16, no.5, pp 490-491, May 2015. 16 references

Samsel, A., Seneff, S. 2015. Glyphosate, pathways to modern diseases IV: Cancer and related pathologies. Journal of Biological Physics and Chemistry 15 (3) 121 - 159. 246 references

Zhang, L., Rana, I., Shaffer, R.M., Taioli, E., Sheppard, L., 2019. Exposure to Glyphosate-Based Herbicides and Risk for Non-Hodgkin Lymphoma: A Meta-Analysis and Supporting Evidence. Mutation Research / Reviews in Mutation Research, available online 10.02.2019. 124 references

Leon, M.E., Schinasi, L.H., Lebailly, P., Freeman, L.E.B., Nordby. K-C., Ferro, G., Monnereau, A., Brouwer, M., Tual, S., Baldi, I., Kjaerham, K., Hofmann, J.N., Kristensen, P., Koutros, S., straif, K., Kromhout, H., Schuz. J. 2019. Pesticide use and risk of non-Hodgkin lymphoid malignancies in agricultural cohorts from France, Norway and the USA: a pooled analysis from the AGRICOH consortium. International Journal of Epidemiology. 53 references

Duforestel, M., Nadaradjane, A., Bougras-Cartron, G., Briand, J., Olivier, C., Frenel, J-S., Vallette, F.M., Lelièvre, S.A., Cartron, P.-F. 2019. Glyphosate Orimes Mammary Cells for Tumorigenesis by Reprogramming the Epigenome in a TET3-Dependent Manner. Frontiers in Genetics, September 2019. 48 references

Portier, C.J., 2020. A comprehensive analysis of the animal carcinogenicity data for glyphosate from chronic exposure rodent carcinogenicity studies. Environmental Health. 19, 18. Published online, Open Access, 12/02/2020. 100 references

Mesnage,R., Ibragim,M., Mandrioli,D., Falcioni,L., Tibaldi,E., Belpoggi,F., Brandsma,I., Bourne,E., Savage,E., Mein,C.A., Antoniou,M.N. 2022. Comparative Toxicogenomics of Glyphosate and Roundup Herbicides by Mammalian Stem Cell-Based Genotoxicity Assays and Molecular Profiling in Sprague-Dawley Rats. Toxicological Sciences, Volume 186, Issue 1, March 2022, pp 83–101, 75 references.

Chang, V.C., Andreotti, G., Ospina,M., Parks, C.G., Liu, D.,  Shearer, J.J., Rothman, N., Silverman, D.T., Sandler, D.P., Calafat, A.M., Beane Freeman, L.E., Hofmann, J.N. 2023. Glyphosate exposure and urinary oxidative stress biomarkers in the Agricultural Health Study. Journal of the National Cancer Institute, Volume 115, issue 4, April 2023. pp. 394-404. 68 references

Rana, J., Nguyen,P.K., Rigutto, G., Louise, A., Lee, J., Smith, M.T., Zhang, L. 2023. Mapping the key characteristicas of carcinogens for glyphosate and its formulations: A systematic review. Chemosphere Vol 339, October 2023. 164 references

Clausing, P., Knasmueller, S., Portier, C.J., 2023. Glyphosate and Oxidative Stress: ECHA's superficial approach neglects existing hazards. zenoob, published August 28 2023.. 56 references

Reprodukcija, trudnoća, urođene mane, smrtnost dojenčadi, poremečaj endokrinog sustava 

Tate, T.M., Spurlock, J.O., Christian, F.A. 1997. Effect of Glyphosate on the Development of Pseudosuccinea columella Snails. Archives of Environmental Contamination and Toxicology. 33 (3) 286-289

Garry, V.F., Harkins, M.E., Erickson, L.L., Long-Simpson, L.K., Holland, S.E., Burroughs, B.L., 2002. Birth Defects, Season of Conception, and Sex of Children Born to Pesticide Applicators Living in the Red River Valley of Minnesota, USA. Environmental Health Perspectives 110 (Suppl 3) 441-449. 69 references

Richard, S., Moslemi, S., Sipahular, H., Benachour, N., Séralini, G-E., 2005. Differential Effects of Glyphosate and Roundup on Human Placenta and Aromatase. Environmental Health Perspectives, 113 (6) 716-720. 38 references

Benachour, N., Sipahular, H., Moslemi, S., Gasnier, C., Travert, C., Séralini, G.E., 2007. Time- and dose-dependent effects of Roundup on Human embryonic and placental cells. Archives of Environmental Contamination and Toxicology 53 (1): 126-133. 42 references

Gasnier, C., Dumont, C., Benachour, N., Clair, E., Chagnon, M.C., Séralini, G.E. 2009. Glyphosate-based herbicides are toxic and endocrine disruptors in human cell lines. Toxicology 262 (3) : 184-191. 94 references

Romano, R.M.., Romano, M.A., 2010. Prepubertal exposure to commercial formulation of the herbicide glyphosate alters testosterone levels and testicular morphology. Archives of Toxicology. 84 (4) 309-317. 40 references 

Antoniou, M., Ezz El-Din Mostafa Habib, M., Howard, C. V., Jennings, R.C., Leifert, C., Nodari, R.O., Robinson, C., Fagan, J.. June 2011. Roundup and birth defects. Is the public being kept in the dark? Pub. Earth Open Source.358 references

Antoniou,M., Habib, M.E.M., Howard, C. V., Jennings, R.C., Leifert, C., Nodari, R.O., Robinson, C., Fagan, J. 2012. Teratogenic Effects of Glyphosate-based Herbicides: Divergence of Regulatory Decisions from Scientific Evidence. Journal of Environmental & Analytical Toxicology, S4-006, 97 references

Romano, M.A., Romano, R.M., Santos, L.D., Wisniewski, P., Campos, D.A., de Souza, P.B., Bernardi, M.M., Nunes, M.T., de Oliviera C.A. 2012. Gyphosate impairs male offspring reproductive development by disrupting gonadotropin expression. Archives of Toxicology, 86 (4) 663-673. 56 references

Kruger, M, Schrodl, Wieland, Pedersen, Ib, & Shehata, A. A., 2014. Detection of Glyphosate in Malformed Piglets. Journal of Environmental and Analytical Toxicology, 4:230 4 references

Young, F., Ho D., Glynn, D., & Edwards, V. 2015. Endocrine disruption and cytotoxicity of glyphosate and roundup in human JAr cells in vitro. Integrative Pharamcology, Toxicology and Genotoxicology. Vol 1 (1) 12-19. 30 references

Parvez, S., Gerona, R. R., Proctor, C., Friesen, M., Ashby, J. L., Reiter, J. L., Lui, Z. & Winchester, P. D. 2018. Glyphosate exposure in pregnancy and shortened gestational length: a prospective Indiana birth cohort study. Environmental Health 2018 17:23. 56 references

Chiu, Y-H., Williams, P.L., Gillman, M., et.al. 2018. Association Between Pesticide Residue Intake From Consumption of Fruits and Vegetables and Pregnancy Outcomes Among Women Undergoing Infertility Treatment With Assisted Reproductive Technology. JAMA Network 178 (1) 17-26.  

Milesi, M.M., Lorenz, V., Pacini, G., Repetti, M.R., Demonte, L.D., Varayoud, J., Luque, E.H. 2018. Perinatal exposure to a glyphosate-based herbicide impairs female reproductive outcomes and induces second-generation adverse effects in Wistar rats. Archives of Toxicology, 92 (8) 2629-2643. 94 references

Avila-Vazquez, M., Difilippo, F.S., Mac Lean, B., Maturano, B., Etchegoyen, A. 2018. Environmental Exposure to Glyphosate and Reproductive Health Impacts in Agricultural Population of Argentina. Journal of Environmental Protection, Open Access Scientific Research, Vol. 9, no.3, March 2018. 36 references

Manservisi, F., Lesseur, C., Panzacchi, S., Mandrioli, D., Falcioni, L., Bua, L., Manservigi, M., Spinaci, M., Galeati, G., Mantovani, A., Lorenzetti, S., Miglio, R., Andrade, A.M., Kristensen, D.M., Perry, M.J., Swan, S.H., Chen, J., Belpoggi, F. 2019. The Ramazzini Institute 13-week pilot study glyphosate-based herbicides administered at human-equivalent dose to Sprague Dawley rats: effects on development and the endocrine system. Environmental Health, 18:15. 54 references

Alarcón, R., Rivera, O.E., Ingaramo, P.I., Tschopp, M.V., Dioguardi, G.H., Milesi, M.M., Muños-de-Toro, M., Luque, E.H. 2020 Neonatal exposure to a glyphosate-based herbicide alters the uterine differentiation of prepubertal ewe lambs. Environmental Pollution, 265 Part B, October 2020, 114874.

Muños, J.P., Bleak, T.C., Calaf, G.M. 2020. Glyphosate and the key characteristics of an endocrine disruptor: A review. Chemosphere online 19th October 2020, 128619. 174 references

Dias, M., Rocha, R., Soares, R.R., 2020. Down the River: Glyphosate Use in Agriculture and Birth Outcomes of Surrounding Populations. Latin American and the Caribbean Economic Association, Working Paper Series 0024. 87 references

Lesseur, C., Pirrotte, P., Pathak, K.V., Manservisi, F., Mandrioli, D., Belpoggi, F., Panzacchi, S., Li, Q., Barrett, E.S., Nguyen, R.H.N., Sathyanarayana. S., Swan, S.H., Chen, J. 2021. Maternal urinary levels of glyphosate during pregnancy and anogenital distance in newborns in a US multicenter pregnancy cohort. Environmental Pollution. 280 1 July 2021, 117002.

Silver, M.K., Fernandez, J., Tang, J., McDade, A., Sabino, J., Rosario, Z., Vélez Vega, C., Alshawabkeh, A., Cordero, J.F., Meeker, J.D. 2021. Prenatal Exposure to Glyphosate and its Environmental Degradate, Aminomethylphosphonic Acid (AMPA), and Preterm Birth: A Nested Case-Control Study in the PROTECT cohort (Puerto Rico). Environmental Health Perspectives Vol. 129, no.5 (Published 19th May 2021). 78 References incorporated into the text

Serra,L., Estienne, A., Vasseur, C., Froment, P., Dupont, J. 2021. Review: Mechanisms of Glyphosate and Glyphosate-Based Herbicides Action in Female and Male Fertility in Human and Animal Models. Cells 10 (11) 3079, November 2021. 113 references

Gerona, R.R., Reiter, J.L., Zakharevich, I., Proctor, C., Ying, J., Mesnage, R., Antoniou, M., Winchester, P.D. 2022. Glyphosate exposure in early pregnancy and reduced fetal growth: a prospective observational study of high-risk pregnancies. Environmental Health 21. Article 95. Published 11th October 2022. 44 references

Hyland, C., Spivak, M., Sheppard, L., Lanphear, B.P., Antoniou, M., Ospina, M., Calafat, A.M., Curl, C.L. 2023. Urinary Glyphosate Concentrations among Pregnant Participants ina Randomized, Crossover Trial of Organic and Conventional Diets. Envirnomental Health Perspectives vol.131, 7, Open Access pub. 26.07.2023. 87 references

Vasseur, C., Serra, L., El Balkhi, S., Lefort, G., Ramé C., Froment, P., Dupopnt, J.  2024. Glyphosate presence in human sperm: First report and positive correlation with oxidative stress in an infertile French population. Ecotoxicology and Environmental Safety, Vo. 278, 15th June 2024. 116410. 100 references

Oštećenje DNK-a, genotoksični učinci

Prasad, S., Srivastava, S., Singh, M., Shukla, Y., 2009. Clastogenic Effects of Glyphosate in Bone Marrow Cells of Swiss Albino Mice. Journal of Toxicology (2009) 308985. 39 references

Koller, V.J., Fürhacker, M., Nersesyan, A., Mišik, M., Eisenbauer, M., Knasmueller, S., 2012. Cytotoxic and DNA-damaging properties of glyphosate and Roundup in human-derived buccal epithelial cells. Archives of Toxicology 86 (5): 805-813. 47 references

Townsend, M., Peck, C., Meng, W., Heaton, M., Robison, R., O'Neill, K. 2017. Evaluation of various glyphosate concentrations on DNA damage in human Raji cells and its impact on cytotoxicity. Regulatory Toxicology and Pharmacology. 85: 79-85.

Kwiatkowska, M., Reszka, E., Wozniak, K., Jablonska, E., Michalowicz, J., Bokowska, B. 2017. DNA damage and methyltaion induced by glyphosate in human peripheral blood mononuclear cells (in vitro study). Food and Chemical Toxicology 105: 93-98.

Santovito, A., Ruberto, S, Gendusa, C., Cervella, P. 2018. In vitro evaluation of genomic damage induced by glyphosate on human lymphocytes. Environmental Science and Pollution Research. Vol. 25, Issue 34, pp 34693-34700. (Online October 2018) 37 references

Benbrook, C.M., 2018. How did the US EPA and IARC reach diametrically opposed conclusions on the genotoxicity of glyphosate-based herbicides? Environmental Sciences Europe, 31:2 (online 14th Janaury 2019. 70 references

Dugoročni trans-generacijski rizici

Kubsad, D., Nilsson, E.E., King, S.E., Sadler-Riggleman, I., Beck, D., skinner, M.E. 2019. Assessment of Glyphosate Induced Epigenetic Transgenerational Inheritance of Pathologies and Sperm Epimutations: Generational Toxicology. Scientific Reports, 9, Article no: 6372. (published 23rd April 2019. 100 references

Maamar, M.B., Beck, D., Nilsson, E.E., Kubsad, D., Skinner, M.K., 2020. Epigenome-wide association study for glyphosate induced transgenerational sperm DNA methylation and histone retention epigenetic biomarkers for disease. Epigenetics 10.1080/15592294.2020.1853319. 41 references

Neplodnost kod muškaraca
 
Clair, E., Mesnage, R., Travert, C., Séralini, G.E., 2012. A glyphosate-based herbicide induces apoptosis in mature rat cells in vitro, and testosterone decrease at lower levels. Toxicology in vitro 26: 269-279. 61 references

de Liz Oliveira Cavalli, V.L., Cattani, D., Heinz Rieg, C.E., Pierozan, P., Zanatta, L., Parisotto, E.B., Filho D.W.., Mena Barreto Silva, F.R., Pessoa-Pureur, R., Zamoner, A., 2013. Roundup disrupts male reproductive functions by triggering calcium-mediated cell death in rat testis and Sertoli cells. Free Radical Biology and Medicine 65: 335-346. 80 references

Liu, J-B., Wang, Z-Y., Wang, L. 2022. Glyphosate damages blood-testis barrier via NOX1-triggered oxidative stress in rats: Long-term exposure as a potential risk for male reproductive health. Environment International 159, 15 January 2022, 107038. 68 references

Plućne tegobe i Astma

Avila-Vázquez, M., Difilippo, F., Mac Lean, B., Maturano, E. 2020. Risk of asthma and environmental exposure to glyphosate in an ecological study. Authorea. August 13, 2020. 30 references

Sidthilaw, S., Sapbamrer, R., Pothirat, C., Wunnapuk, K, Khacha-ananda, S. 2022. Effects of exposure to glyphosate on oxidativ stress, inflammation and lung function in maize farmers, Northern Thailand. BMC Public Health, Article no. 1343. 49 References

Poremečaj crijevne mikroflore

Brewster, D.W., Warren, J.,Hopkins, W.E., 1991. Metabolism of glyphosate in Sprague-Dawley rats: Tissue distribution, identification, and quantification of glyphosate-derived materials following a single oral dose. Fundamental and Applied Toxicology 17: 43-51

Shehata, A. A., Schrödl, W., Aldin, A. A., Hafez, H. M., Krüger, M., 2012. The effect of Glyphosate on potential pathogens and beneficial members of poultry microbiotica in vitro. Current Microbiology, 9th December 2012. 59 references

Samsel, Anthony & Seneff, Stephanie 2013. Glyphosate, pathways to Modern Diseases II: Celiac Sprue and Gluten Intolerance. Interdisciplinary Toxicology 6 (4) 159-184. 271 references

Samsel, Anthony, Seneff, Stephanie, 2013. Glyphosate's Suppression of Cytochrome P450 Enzymes and Amino Acid Biosynthesis by the Gut Microbiome: Pathways to Modern Diseases. Entropy 15: 1416-1463. 286 references

Schrödl, W., Krüger, S., Konstantinova-Müller, T., Shehata, A., Rulff, R., Krüger, M., 2014. Possible Effects of Glyphosate on Mucorales Abundance in the Rumen of Dairy Cows in Germany. Current Microbiology 69 (6) 817-823. 40 references 

Mao, Q, Manservisi, S., Panzacchi, S., Mandrioli, D., Menghetti, I., Vornoli, A., Buia, L., Falcioni, L., Lesseur, C., Chen, J., Belpoggi, F., Hu, J. 2018. The Ramazzini Institute 13-week pilot study on glyphosate and Roundup administered at human-equivalent dose to Sprague Dawley rats: effects on the microbiome. Environmental Health, 17:50. 80 references

Mesnage, R., Teixeira, M.,Mandrioli, D., Falcioni, L., Ducarmon, Q.R., Zwittink, R.D., Amiel, C., Panoff, J-M., Belpoggi, F., Antoniou, M.N. 2019. Shogun metagenomics reveal glyphosate alters the gut microbiome of Sprague-Dawley rats by inhibiting the shikimate pathway. bioRxiv - preprint (prior to peer review) posted 11th December 2019. 74 references

Barnett, J.,A., Gibson, D.L. 2020. Separating the Empirical Wheat from the Pseudoscientific Chaff: A Critical Review of the Literature Surrounding Glyphosate, Dsybiosis and Wheat-Sensitivity. Frontiers in Microbiology. 25 September 2020. 47 references

Leino, L., Tall, T., Helander, M., Saloniemi, I., Saikkonen, K., Ruuskanen, S., Puighò, P. 2020. Classification of the glyphosate target enzyme (5-enolpyruvylshikimate-3-phosphate synthase) for assessing sensitivity of organisms to the herbicide. Journal of Hazardous Materials, online November 2020, 124556. 49 references

Mesnage, R., Teixeira, M., Mandrioli, D., Falcioni, L., Ducarmon, Q.R., Zwittink, R.D., Mazzacuva, F., Caldwell, A., Amiel, C., Pannoff, J-M., Belpoggi, F., Antoniou, M.N. 2021. Use of Shotgun Metagenomics and Metabolomics to Evaluate the Impact of Glyphosate or Roundup MON 52276 on the Gut Microbiota and Serum Metabolome of Sprague-Dawley Rats.. Environmental Health Perspectives Vol. 129, no.1 (January 2021) References incorporated in text

Mesnage, R., Calatayud, M., Duysburgh, C., Marzorati, M. and Antoniou, M.N. 2022. Alterations in infant gut microbiome composition and metabolism after exposure to glyphosate and Roundup and/or a spore-based formulation using the SHIME technology. Gut Microbiome. Published online by Cambridge University Press, 26 July 2022. 73 references

Šteta na organima (osobito bubrezima i jetrima)

Jayasumana, C., Gunatilake, S., Senanayake, P., 2014. Glyphosate, Hard Water and Nephrotoxic Metals: Are They the Culprits Behind the Epidemic of Chronic Kidney Disease of Unknown Etiology in Sri Lanka? International Journal of Environmental Research and Public Health. 109 references

Séralini, G-E, Clair, E., Mesnage, R., Gress, S., Defarge, N., Malatesta, M., Hennequin, D., Spiroux de Vendômois, J., 2014. Republished study: long-term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize. Environmental Sciences Europe, 26: 14. 75 references

Tizhe, E.V., Onyebuche, I.I., George, B.D.J., Ambali, S.F., Shallangwa, J.M., 2014. Influence of zinc supplementation on histopathological changes in the stomach, liver, kidney, brain, pancreas and spleen during subchronic exposure of Wistar rats to glyphosate. Comparative Clinical Pathology 23 (5): 1535-1543 (published online October 2013) 32 references

Jayasumana, C., Paranagama, P., Agampodi, S., Wijewardane, C., Gunatilake, S., Siribaddana, S., 2015. Drinking well water and occupatiomal exposure to Herbicides is associated with chronic kidney disease, in Padavi-Sripura, Sri Lanka. Environmental Health 14:6. 41 references

Jayasumana, C., Gunatilake, S., Siribaddana, S., 2015. Simultaneous exposure to multiple heavy metals and glyphosate may contribute to Sri Lankan agricultural nephropathy. BMC Nephrology 16:103. 47 references

Mesnage, R., Arno, M., Costanzo, M., Malatesta, M., Séralini, G.-E., Antoniou, M.N. 2015. Transcriptome profile analysis reflects rat liver and kidney damage following chronic ultra-low dose Roundup exposure. EnvironmentalHealth 14:70. 44 references

Mesnage, R., Renney, G., Séralini, G.-E., Ward, M., & Antoniou, M. N. 2017. Multiomics reveal non-fatty liver disease in rats following chronic exposure to an ultra-low dose of Roundup herbicide. Nature.com - Scientific reports 7, article number 39328. Published online 9th January 2017. 53 references

Ford, B., Bateman, L.A., Gutierrez-Palominos, L., Park, R., Nomura, D.K. 2017. Mapping Proteome-wide Targets of Glyphosate in Mice. Cell Chemical Biology. 33 references

Gunatilake, S., Seneff, S., Orlando, L. 2019. Glyphosate's Synergistic Toxicity in Combination with Other Factors as a Cause of Chronic Kidney Disease of Unknown Origin. International Journal of Environmental Research and Public Health. 16 (15): 2734. 167 references

Trasande, L., India-Aldana, S., Trachtmn, H., Kannan, K., Morrison, D., Christakis, D.A., Whitlock, K., Messito, M.J., Gross, R.S., Karthikraj, R., Sathyanarayana, S. 2020. Glyphosate Exposures and Kidney Injury Biomarkers in Infants and Young Children. Environmental Pollution 256: 113334. Published online October 23rd 2019 doi: 10.1016/j.envpol.2019.113334. 46 references

Qi, L., Dong, Y-M., Chao, H., Zhao, P., Ma, S-L., Li, G., 2023. Glyphosate-based herbicide disrupts energy metabolism and activates inflammatory response through oxidative stress in mice liver. Chemosphere vol. 315 February 2023, 137751. 64 references

Eskenazi, B., Gunier, R.B., Rauch, S., Kogut, K., Perito, E.M., Mendez, X., Limbach, C., Holland, N., Bradman, A., Harley, K.G., Mills, P.J., Mora, A.M. 2023. Association of Lifetime Exposure to Glyphosate and Aminomethylphosphonic Acid (AMPA) with Liver Inflammation and Metabolic Syndrome at Young Adulthood: Findings from the CHAMACOS Study. Environmental Health Perspectives vol.131 no.3. March 2023. 93 references

Unos hranom, glifosat prisutan u mokraći, te u majčinom mlijeku

Hoppe, H-W., 2013. Determination of Glyphosate residues in Human urine samples from 18 European countries. Study of 182 urine samples carried out at the Medical Laboratory Bremen, Germany, sponsored by BUND & FoE

Krüger, M., Schledorn, P., Schrödl, W., Hoppe, H-W., Lutz, W., Shehata, A.A., 2014.Detection of Glyphosate Residues in Animals and Humans. Journal of Environmental and Anayltical Toxicology4: 210. 30 references

Schrödl, W., Krüger, S., Konstantinova-Müller, T., Shehata, A., Rulff, R., Krüger, M., 2014. Possible Effects of Glyphosate on Mucorales Abundance in the Rumen of Dairy Cows in Germany. Current Microbiology 69 (6) 817-823. 40 references

Honeycutt, Z., Rowlands, H., 2014. Glyphosate testing report:Findings in American Mothers' Breast Milk, Urine and Water. Research conducted by Moms Across America & Sustainable Pulse. 6 references, plus listing of ten relevant scientific papers with online links.

Mills, P.J., Kania-Korwel, I., Fagan, J., et al. 2017. Excretion of the Herbicide Glyphosate in Older Adults between 1993 asnd 2016. JAMA Network (Journal of the American Medical Association) 318 (16) 1610-1611

Neurološka oštećenja

Paganelli, A., Gnazzo, V., Acosta, H., Lopez, S.L., & Carrasco, A.E., 2010. Glyphosate-based herbciides produce teratogenic effects on vertebrates by impairing retinoic acid signalling. Chemical Research in Toxicology, 18: 23 (10): 1586 - 95, 99 references

Cattani, D., de Liz Oliveira Cavalli V.L., Rieg, C.E.H., Dominques, J.T., Dal-Cim, T., Tasca, C.I., Barreto Silva, F.R.M., Zamoner, A., 2014. Mechanisms underlying the neurotoxicity induced by glyphosate-based herbicide in immature rat hippocampus: involvement of glutamate excitoxicity. Toxicology 320 (5): 34-45. 53 references

Samsel,A., Seneff,S. 2015. Glyphosate pathways to modern diseases III: Manganese, neurological diseases, and associated pathologies. Surgery Neurology International, 6:45. 8 references

Winstone, J.K., Pathak, K.V., Winslow, W., Piras, I.S., White, J., Sharma, R., Huentelman, M.J., Pirrotte, P., Velasquez, R. 2022. Glyphosate infiltrates the brain and increases pro-inflammatory cytokine TNFα: implications for neurodegenerative disorders. Journal of Neuroinflammation 19, 193. 77 references

Hsiao, C.C., Yang, A-M., Wang, C., Lin, C-Y. 2023. Association between glyphosate exposure and cognitive function, depression, and neurological diseases in a representative sample of US adults: NHANES 2013-2014 analysis.  Environmental Research vol. 237, Part 1, 15.11.2023. 59 references

Yang, A-M., Chu, P-L., Wang, C., Lin, C-L. 2023. Association between urinary glyphosate levels and serum neurofilament light chain in a representative sample of US adults: NHANES 2013 - 2014. Journal of Exposure Science & Environmental Epidemiology, publioshed September 6th 2023. 54 references

Parkinsonova bolest

Barbosa E.R., da Costa, L., Bacheschi, L.A., Scaff, M., Leite, C.C., 2001. Parkinsonism after glycine-derivate exposure. Movement Disorders 16 (3): 565-568

Caballero, M., Amiri, S., Denney, J.T., Monsivais, P., Hystad, P. 2018. Estimated Residential Exposure to Agricultural Chemicals and Premature Mortality by Parkinson's Disease in Washington State. International Journal of Environmental Research and Public Health 15 (12) 2885. 40 references

Autizam

de Cock, M., Maas, Y.G., van de Bor, M., 2012. Does perinatal exposure to endocrine disruptors induce autism spectrum and attention deficit hyperactivity disorders? Review. Acta Paediatrica 101 (8): 811-888. 55 references

von Ehremstein, O.S., Ling, C., Cui, X., Cockburn, M., Park, A.S., Yu F., Wu, J. 2019. Prenatal and infant exposure to ambient pesticides and autism spectrum disorder in children: population based case-control study. British Medical Journal; 364:1962. 80 references

ŽIVOTINJE

Talyn, B., Muller, K., Mercado, C., Gonzalez, B, Bartels, K. 2023. The Herbicide Glyphosate and Its Forumlations Impact Animal Behavior across Taxa.  Agrochemicals 2023, 2 (3) 367-408. Pub. 10.07.2023. 223 references

UTJECAJI NA OKOLIŠU

Cox, C., 1995. Glyphosate, Part 2: Human Exposure and Ecological Effects. Journal of Pesticide Reform 15 (4) 78 references

Buffin, D., Jewell, T., 2001.Health and environmental impacts of glyphosate: The implications of increased use of glyphosate in association with genetically modified crops. Pub. Friends of the Earth UK. 117 references

Hébert, M-P., Fugère, V., Gonzalez, A. 2018. The overlooked impact of rising glyphosate use on phosphorus loading in agricultural watersheds. Frontiers in Ecology and the Environment. 59 references

Kruse-Plaß, M., Hofmann, F., Wosniaok, W., Schlechtriemen, U., Kohlschlütter, N. 2021. Pesticides and pesticide-related products in ambient air in Germany. Environmental Sciences Europe, 33, article number 114. 46 references

VODA, RIBE, VODENI ORGANIZMI

Folmar, L.C., Sanders, H.O., Julin, A.M. 1979. Toxicity of the herbicide glyphosate and several of its formulations to fish and aquatic invertebrates. Archives of Environmental Contamination and Toxicology 8 (3) 269-278. 9 references

Popp, M., Hann, S., Mentler, A., Fuerhacker, M., Stingeder, G., Koellensperger, G., 2008. Determination of glyphosate and AMPA in surface and waste water using high-performance ion chromatography coupled to inductively coupled plasma dynamic reaction celll  mass spectrometry (HPIC-ICP-DRC-MS). Analytical and Bioanalytical Chemistry 391 (2): 695-699. 16 references

Cummings,M., Bullerjahn, G.S. 2009. Phosphate Utilization by Great Lakes (Cyanobacteria). Vermont Government Agency (Poster)

Bullerjahn,G.S. 2010. Glyphosate loadings in Lake Erie Watersheds. Final report for LEPF Award 09-357. (Data collected through field studies)

Strickland,T., Fisher, L., Korleski, C. / Phosphorus Task Force. 2010. Ohio Lake Erie Phosphorus Task Force Final Report. Ohio Environmental Protection Agency. 126 references. (p.41, 4.2.1.6. Glyphosate as a Source of Phosphorus) 

Sanchis,J., Kantiani, L., Llorca, M., Rubio, F., Ginebreda, A., Fraile, J., Garrido, T., Farré, M., 2012. Determination of glyphosate in groundwater samples using an ultrasensitive immunoassay and confirmation by on-line solid-phase extraction followed by liquid chromatography coupled to tandem mass spectrometry. Analytical and Bioanalytical Chemistry 402 (7) 2336-2345. 25 references

Shiogiri, N.S., Paulino, M.G., Carraschi, S.P., Baraldi, F.G., da Cruz, C.,Fernandes, M.N., 2012. Acute exposure of a glyphosate-herbicide affects the gills and liver of the Neotropical fish, Piaractus mesopotamicus. Environmental Toxicology and Pharmacology 34 (2) 388-396

Nwani, C.D., Nagpure, N.S., Kumar, R., Kushwaha, B., Lakra, W.S., 2013. DNA damage and oxidative stress modulatory effects of glyphosate-based herbicide in freshwater fish Channa punctatus. environmental Toxicology and Pharmacology 36 (2) 539-547. 15 references

Ruiz-Toledo, J., Castro, R., Rivéro-Perez, N., Bello-Mendoza, R., Sánchez, D., 2014. Occurrence of Glyphosate in Water Bodies Derived from Intensive Agriculture in a Tropical Region of Southern Mexico. Bulletin of Envirnomental Contamination and Toxicology 93 (3): 289-293. 47 references

Mercurio, P., Flores, F., Mueller, J.F., Carter, S., Negri, A.P., 2014. Glyphosate persistence in seawater. Marine Pollution Bulletin 85 (2) 385-390. 53 references

Wang,C., Lin X., Li,L., Lin, S., 2016. Differential Growth Responses of Marine Phytoplankton to Herbicide Glyphosate. PLoS One. 86 references

Roy, N.M., Carneiro, B., Ochs, J. 2016. Glyphosate induces neurotoxicity in zebrafish. Environmental Toxicology and Pharamcology, 42: 45-54. 

Hébert, M.-P., Fugère, V., Gonzalez, A. 2018. The overlooked impact of rising glyphosate use on phosphorus loading in agricultural watersheds. Frontiers in Ecology and the Environment (The Ecological Society of America) 17 (1): 48 - 56. 59 references 

Bruno Bastos Gonçalves, Percilia Cardoso Giaquinto, Douglas dos Santos Silva, Carlos de Melo e Silva Neto, Amanda Alves de Lima, Adriano Antonio Brito Darosci, Jorge Laço Portinho, Wanessa Fernandes Carvalho and Thiago Lopes Rocha, 2019.  Ecotoxicology of Glyphosate-Based Herbicides on Aquatic Environment. 108 references. Open access peer-reviewed chapter, from 'Biochemical Toxicology' by Ince M., Ince, O.K., Ondrasek, G., pub. July 2020, open access e-book. 

Fugère, V., Hébert, M-P., Barbosa da Costa N., Xu, C.C.Y., Barrett, R.D.H., Beisner, B.E., Bell, G., Fussmann, G.F., Shapiro B.J., Yargeau, V., Gonzalez, A. 2020. Community rescue in experiemntal phytoplankton communities facing severe herbicide pollution. Nature Ecology and Evolution, 1134-5. 81 references

Sánchez, J.A.A., Barros, D.M., Bistoni, M. de los Angeles, Ballesteros, M.L., Roggio, M.A., Martins, C De Gaspar Martinez. 2021. Glyphosate-based herbicides affect behavioural patterns of the livebearer Jenynsia multidentata. Environmental Science and Pollution Rsearch. Published 12th February 2021. 85 references

da Costa, N.B., Hébert, M-P., Fugère, V., Terrat, Y., Fussmann, G.F., Gonzalez,A., Shapiro, J. 2022. A glyphosate-based herbicide cross-selects for antibiotic resistance genes in bacterioplankton communities. ASM journals (American Society for Microbiology) 56 references

TLO, KOPNENI ORGANIZMI

Correia, F.V., Moreira, J.C., 2010. Effects of Glyphosate and 2,4-D on Earthworms (Eisenia foetida) in Laboratory Tests. Bulletin of Environmental Contamination and Toxicology 85 (3): 264-268
 
Gaup-Berghausen M,  Hofer M,  Rewald B, Zaller JG 2015. Glyphosate-based herbicides reduce the activity and reproduction of earthworms and lead to increased soil nutrient concentrations. Scientific Reports Nature.com 5: 12886. Published online 05.08.2015. 47 references 
 
Bento, C.P.M., Yang, X., Gort, G., Xue, S., van Dam, R., Zomer, P., Mol, H.G.J., Ritsema, C.J., Geissen, V., 2016. Persistence of glyphosate and aminomethylphosphonic acid in loess soil under different combinations of temperature, soil moisture and light/darkness. Science of the Total Environment, Vol. 572, 301-311
 
Aristilde, L., Reed, M.L., Wilkes,R.A., Youngster, T., Kukurugya, M.A., Katz, V., Sasaki, C.R.S. 2017. Glyphosate-Induced Specific and Widespread Perturbations in the Metabolome of Soil Pseudomonas Species. Fronteirs in Environmental Science (20th June 2017).  42 references
 
Kremer, R.J. 2017. Soil and Environmental Health After Twenty Years of Intensive Use of Glyphosate. Advances in Plants and Agriculture Research 6 (5): 00224. DOI: 10.15406/apar.2017.06.00224; Online PDF: MedCrave, (7th March 2017). 14 references
 
Silva, V., Mol, G.J., Zomer, P., Tienstra, M., Ritsema, C.J., Geissen, V., 2018. Pesticide residues in European agricultural soils - A hidden reality unfolded. Science of the Total Environment, 653: 1532-1545. (25.02.2019). 49 references 
 
Kanissery, R., Gairhe, B., Kadyampakeni, D., Batuman, O., Alferez, F. 2019. Glyphosate: Its Environmental Persistence and Impact on Crop Health and Nutrition. MDPI Plant Protection and Biotic Interactions Section. 83 references

Liao, H., Li, X., Yang, Q., Bai, Y., Cui, P., Wen, C., Liu, C., Chen, Z., Tang, J., Che, J., Yu, Z., Geisen, S., Zhou, S., Friman, V-P., Zhu, Y-G. 2021. Herbicide Selection Promotes Antibiotic Resistance in Soil Microbiomes. Molecular Biology and Evolution. Vol 38 issue 6 pp 2337 - 2350.  June  2021. 75 references

da Silva, K.A., Nicola, V.B., Dudas, R.T., Demetrio, W.C., dos Santos Maia, L., Cunha, L., Bartz, M.L.C., Brown, G.G., Pasini, A, Kille, P., FGerreira, N.G.C., de Oliveira, C.M.R. 2021. Pesticides in a case study on no-tillage farming systems and surrounding forest patches in Brazil. Nature, Scientific Reports 11, article number 9839, published 10th May 2021. 110 references

Naraine, A., Sweeney, I., Aker, R., Shanbhag, V., Dawson-Scully, K. 2021. Roundup and Glyphosate Exposure Elicits Proconvulsant Behaviour in C.elegans. Federation of American Societies for Environmental Ecoloy (FASEB)  Vol. 35, issue 51, article first published 14th May 2021.

Owagboriaye, F., Mesnage, R., Dedeke, G., Adegboyeda, T., Aladesida, A., Adeleke, M., Owa, S., Antoniou, M.N. 2021. Impacts of a glyphosate-based herbicide on the gut microbiome of three earthworm species (Alma millsoni, Eudrilus eugeniae, and Libyodrilus violaceus): A pilot study. Toxicology Reports 8 (2021) 753-758. 52 references

Hanpeng Liao, Xi Li, Qiue Yang, Yudan Bai, Peng Cui, Chang Wen, Chen Liu, Zhi Chen, Jiahuan Tang, Jiangang Che, Zhen Yu, Stefan Geisen, Shungui Zhou , Ville-Petri Friman , Yong-Guan Zhu 2021. Herbicide Selection Promotes Antibiotic Resistance in Soil Microbiomes. Molecular Biology and Evolution Vol 38 issue 6 pp 2337 - 2350, June 2021. 75 references

DRVEĆE

Feucht, J.R. 1988. Herbicide injuries to trees - symptoms and solutions. Journal of Arboriculture 14 (9) 215-219 (page 217). 8 references

BILJKE

Hawkes, T.R., Lorraine-Colwill, D.F., Williams, P.H., Warner, S.A.J., Sutton, P.B., Powles, S.B., Preston, C., 1999. Resistance to Glyphosate in a Population of Lolium Rigidum. Plant Biotechnology and in vitro Biology in the 21st Century. Current Plant Science and Biotechnology in Agriculture. 36: 491-494 10 references

Bott, S., Tesfamariam, T., Candan, H., Cakmak, I., Römheld, V., Neumann, G., 2008. Glyphosate-induced impairment of plant growth and micronutrient status in glyphosate-resistant soybean (Plant and Soil 312 (1-2): 185-194

Fernandez, M.R., Zentner, R.P., Basnyat, P., Gehl, D., Selles, F., Huber, D., 2009. Glyphosate associations with cereal diseases caused by Fusarium spp. in the Canadian prairies. European Journal of Agronomy 31: 133-143. 63 references 

Kremer, R.J., Means, N.E., 2009. Glyphosate and glyphosate-resistant crop interactions with rhizosphere microorganisms. European Journal of Agronomy 31 (3) 153-161. 

Johal, G.S., Huber, D.M., 2009. Glyphosate effects on diseases of plants. European Journal of Agronomy 31 (3): 144-152. 72 references

Fuchs, B., Saikkonen,K., Helander,M. 2020. Glyphosate-Modulated Biosynthesis Driving Plant Defense and Species Interasctions. Trends in Plant Science, 26, issue 4, 312-313 (April 2021). Open Access published 02/12/2020.  86 references

Golt, A.R., Wood, L.J., 2021. Glyphosate-Based Herbicides Alter the Reproductive Morphology of Rosa acicularis (Prickly Rose). Frontiers in Plant Science. 45 references

Botteri, N., Wood, L.J., Werner, J.R. 2021. Glyphosate remains in forest plant tissues for a decade or more. Forest Ecology and Management vol.493, published 1st August 2021. 53 references

PČELE

Goodwin, R.M., and McBrydie, H.M. 2000. Effect of Surfactants on Honey Bees, New Zealand Plant Protection 53 (August 1, 2000): 230–234.

Gill, R.J., Ramos-Rodriguez, O., Raine, N.E., 2012 Combined pesticide exposure severely affects individual- and colony-level traits in bees. Nature 491: 105-108. 40 references, 20 supplementary references

Boily, M., Sarrasin, B., DeBlois, C., Aras, P., Chagnon, M. 2013. Acetylcholinesterase in honey bees (Apis mellifera) exposed to neonicotinoids, atrazine and glyphosate: laboratory and field experiments, Environmental Science and Pollution Research 20, 5603–5614 (2013). 45 references

Herbert, L.T., Vázquez, D.E., Arenas, A., Farina, W.M., 2014. Effects of field-realistic doses of glyphosate on honeybee appetite behaviour. Journal of Experimental Biology 217: 3457-3464. 52 references

Balbuena, M.S., Tison, L., Hahn, M-L., Greggers, U., Menzel, R., Farina, W.M., 2015. Effects of sublethal doses of glyphosate on honeybee navigation, Journal of Experimental Biology 218 (17) 2799-2805. 47 references

Motta, E.V.S., Raymann, K., Moran, N.A. 2018. Glyphosate perturbs the gut microbiotica of honey bees. Proceedings of the National Academy of Sciences (PNAS) of the United States of America, published online ahead of print, September 24 2018. 47 references

Abraham, J., Senami Benhotons, G., Krampah, I., Tagba J., Amissah, C., Dwomoh Abraham, J. 2018. Commercially formulated glyphosate can kill non-target pollinator bees under laboratory conditions, Entomologia Experimentalis et Applicata 186 (8) 695-702

Motta, E.V.S., Raymann, K., Moran, N.A. 2018. Glyphosate perturbs the gut microbiota of honey bees, Journal of Applied Biological Sciences. 115 (41) 10305–10310. 47 references

Vázquez, D.E., Ičina, N., Pagano, E.A., Zavala, J.A., Farina, W.M. 2018. Glyphosate affects the larval development of honey bees depending on the susceptibility of colonies, PLoS ONE 13 (October 9 2018) e0205074. 67 references

Blot, N., Veillat, L., Rouzé, R., Delatte, H. 2019. Glyphosate, but not its metabolite AMPA, balters the honeybee gut microbiota, PLoS ONE 14 (4) e0215466. 58 references

Farina, W.M., Balbuena, M.S., Herbert, L.T., Mengoni Gonalons, C., Vasquez, D.E. 2019. Effects of the herbicide glyphosate on honey bee sensory and cognitive abilities: Individual impairments with implications for the hive, Insects, 10 (19) 354. 85 references

Zgurzynski, M., and Lushington, G. 2019. Glyphosate Impact on Apis mellifera Navigation: A Combined Behavioral and Cheminformatics Study. Pharmacology and Toxicology 7 (8) (July 2019): 806-824. 41 references

Daisley, B.A., Chmiel, J.A., Pitek, A.P., Thompson, G.J., Reid, G. 2020. Missing Microbes in Bees: How Systematic Depletion of Key Symbionts Erodes Immunity. Trends in Microbiology (2020) 28 (12), 1010-1021, 103 references

El Agrebi, N., Tosi, S., Wilmart, O., Scippo, M-L., de Graaf, D.C., Saegerman, C., 2020. Honeybee and consumer’s exposure and risk characterisation to glyphosate-based herbicide (GBH) and its degradation product (AMPA): Residues in beebread, wax, and honey, Science of The Total Environment, Volume 704, 20th February 2020, 135312. ISSN 0048-9697.

Faita, M.R., Cardozo, M.M., Amandio, D.T.D. 2020. Glyphosate-based herbicides and Nosema sp. microsporidia reduce honey bee (Apis mellifera L.) survivability under laboratory conditions. Journal of Apicultural Research 59 332–342, 81 references

Ledoux, M.L., Hettiarachchy, N., Yu, A., Howard, L., Sun-Ok, L. 2020. Penetration of glyphosate into the food supply and the incidental impact on the honey supply and bees, Food Control (2020) 109: 106859. 86 references

Motta, E.V.S. Moran, N.A. 2020. Impact of glyphosate on the honey bee gut microbiota: effects of intensity, duration, and timing of exposure, ASM Journals, mSystems vol. 5 no. 4 (28 July 2020) 59 references

Vázquez, D.E., Balbuena M.S., Chaves, F., Gora, J., Menzel, R., Farina, W.M. 2020. Sleep in honey bees is affected by the herbicide glyphosate, Scientific Reports 10 (29 June 2020) 10516.

Luo, Q-H., Gao, J., Liu, C., Ma, Y-Z., Zhou, Z-Y., Dai, P-L., Hou, C-S., Wu, Y-Y., Diao, Q-Y. 2021. Effects of a commercially formulated glyphosate solutions at recommended concentrations on honeybee (Apis mellifera L.) behaviours, Scientific Reports 11 (2021) 2115, 54 references

Straw, E.A., Carpentier, E.N., Brown, M.J.F. 2021. Roundup causes high levels of mortality following contact exposure in bumble bees. Journal of Applied Ecology 06.04.2021. 61 references

Almasri, H., Tavares, D.A., Tchamitchian, S., Pélissier, M., Sené, D., Cousin, M., Brunet, J-L., Belzunces, L.P., 2021. Toxicological status changes the
susceptibility of the honey bee Apis mellifera to a single fungicidal spray application, Environmental science and Pollution Research. 28, 42807–42820 (6th April 2021), 94 references.

Graffigna, S., Marrero, H.J., Torretta, J.P. 2021. Glyphosate commercial formulation negatively affects the reproductive success of solitary wild bees in a Pampean agroecosystem, Apidologie, 52, 272–281 (2021). 48 references

Battisti, L., Potrich, M., Sampaio, A.R., de Castillo Ghisi, N., Costa-Maia, F., Abati, R., Bueno dos Reis Martinez, C.Sofia,S.H. 2021. Is glyphosate toxic to bees? A meta-analytical review, Science of the Total Environvironment 767 (1st May 2021) 145397

Straw, E.A., Carpentier, E.N., Brown, M.J.F. 2021 Roundup causes high levels of mortality following contact exposure in bumble bees, Journal of Applied Ecology. 58 (06 April 2021) 1167–1176, 61 references

Motta,E.V.S., Powell, J.E., Moran, N.A. 2022. Glyphosate induces immune dysregulation in honey bees, Animal Microbiome 4 (2022) 16. 77 references

Tan, S., Li, G., Liu, Z., Wang, H., Guo, X., Xu, B. 2022. Effects of glyphosate exposure on honeybees. Environmental Toxicology and Pharmacology. 90. 3792. 106 references

Dai, P., Yan, Z., Ma, S., Yang, Y., Wang, Q., Hou, C., Wu, Y., Liu, Y., Diao, Q. 2018. The Herbicide Glyphosate Negatively Affects Midgut Bacterial Communities and Survival of Honey Bee during Larvae Reared in Vitro, Journal of Agricultural and Food Chemistry. (2018), 66, 29, 7786–7793

da Silva, P.C., Goncalves, B., Franceschinelli, E., Brito, P. et al., 2022. Glyphosate-Based Herbicide Causes Cellular Alterations to Gut Epithelium of the Neotropical Stingless Bee Melipona quadrifasciata quadrifasciata (Hymenoptera: Meliponini), Neotropical Entomology (15 Nov 2022) 51(6):860-868. 19 references

Tan, S., Li, G., Liu, Z., Wang, H., Guo, X., Xu, B. 2022. Effects of glyphosate exposure on honeybees, Environmental Toxicology and Pharmacolpgy. 90 (February 2022) 103792.Weidenmüller,A., Meltzer, A., Neupert, S.,

Schwartz, A., Kleineidam, C. 2022. Glyphosate impairs collective thermoregulation in bumblebees, Science 376 issue 6597 (2 July 2022) 1122–1126.85 references 

Zioga, E., White, B.,Stout, J.C. 2022. Glyphosate used as desiccant contaminates plant pollen and nectar of non-target plant species, Heliyon, vol. 8 issue 12 e12179 (December 07 2022). 163 references

Wang, B., Habermehl, C., Jiang, L. 2022. Metabolomic analysis of honey bee (Apis mellifera L.) response to glyphosate exposure, Molecular Omics, issue 7, 2022

Helander, M., Lehtonen, T.K., Saikkonen, K., Despains, L., Nyckees, D., Antinoja, A., Solvi, C., Loukola, O.J. 2023. Field-realistic acute exposure to glyphosate based herbicide impairs fine-color discrimination in bumblebees, Science of the Total Environment, (2023) 857(Pt 1):159298. 40 references

Motta,E.V.S. Moran, N.A. 2023. The effects of glyphosate, pure or in herbicide formulation, on bumble bees and their gut microbial communities. Science of the Total Environment. 872: 162102.

Nouvian, M., Foster, J.J., Weidenmüller, A., 2023. Glyphosate impairs aversive learning in bumblebees. Science of The Total Environment vol. 898, 10.11.2023. 72 references

LEPTIRI

Sirinathsinghji, E., 2011. Glyphosate and Monarch Butterfly Decline. Report for the Institute of Scientists in Society, 19/9/2011.

Pleasants, J.M., Oberhauser, K.S., 2012. Milkweed loss  in agricultural fields because of herbicide use: effect on the monarch butterfly population. Insect Conservation and Diversity 6 (2): 135-144. 33 references

Taylor, O. R. Jr, Pleasants, J.M., Grundel, R., Pecoraro, S.D., Lovett, J.P., Ryan, A. 2020. Evaluating the Mogration Mortality Hypothesis Using Monarch Tagging Data. Frontiers in Ecology and Evolution. (Online 07.08.2020) 49 references

Vazquez, D.E., Villegas Martinez, L.E., Medina, V., Latorre-Estivalis, J.M., Zavala, J.A., Farina, W.M., 2023. Glyphosate affects larval gut microbiota and metamorphosis of honey bees with differences between rearing procedures. Environmental Pollution vol.334, 01.10.2023. 99 references

KUKCI

Kiefer, J.S.T., Batsukh, S., Bauer, E., Hirota, B., Weiss, B., Wierz, J., Fukatsu, T., Kaltenpoth, M., Engl, T. 2021. Inhibition of  a nutritional endosymbiont by glyphosate abolishes mutualistic benefit on cuticle synthesis in Oryzaephilus surinamensis. Communications Biology 4, article 554, published 11th May 2021. 123 references

Smith, D.F.Q., Camacho, E., Thakur, R., Barron, A.J., Deng, Y., Dimopoulos, G., Broderick, N.A., Casadevall, A. 2021. Glyphosate inhibits melanization and increases susceptibility to infection in insects. PLOS Biology. published 12th May 2021. 139 references

GASTROPODA (PUŽEVI)

Tate, T.M., Spurlock, J.O., Christian, F.A. 1997. Effect of Glyphosate on the Development of Pseudosuccinea columella Snails. Archives of Environmental Contamination and Toxicology. 33 (3) 286-289

Herbicid u vinogradu u Starogradskom polju. Foto: Vivian Grisogono

DOKAZI DA HERBICIDI NA BAZI GLIFOSATA NISU ŠTETNI

?

Počinje se uveliko sumnjati na integritet znanstvenika i drugih, koji pišu članke potpore za Glifosat. Budući da agro-kemijski biznis donosi ogromne profite širom svijeta, u igri je mnogo. Nije iznenađujuće ako su tvrtke spremne platiti za podršku, niti da su neki utjecajni ljudi spremni prihvatiti novac u zamjenu za svoju potporu.

Kada je glifosat bio provjeravan od strane Agencije za Zaštitu Okoliša Sjedinjenih Država, popratna dokumentacija nije sadržavala nikakve članke iz recenziranih časopisa. Onih nekoliko objavljenih radova na popisu uglavnom su se bavila laboratorijskim protokolima. Inače se velika većina "pratećih dokaza" sastojala od neobjavljenih radova sponzoriranih od strane agro-kemijskih tvrtki koje su tražili ponovnu registraciju proizvoda.

Pripremila Vivian Grisogono 2016: tekst redovno ažuriran, zadnji put u svibnju 2024..

Video sadržaj

Nalazite se ovdje: Home opasni otrovi Herbicidi na bazi glifosata: znanstveni radovi

Eco Environment News feeds

  • Wheat haul in England estimated to be down by 21%, with Britain’s wine producers also hit hard

    England has suffered its second worst harvest on record – with fears growing for next year – after heavy rain last winter hit production of key crops including wheat and oats.

    The cold, damp weather, stretching from last autumn through this spring and early summer, has hit the rapidly developing UK wine industry particularly hard, with producers saying harvests are down by between 75% and a third, depending on the region.

    Continue reading...

  • With clean air projects receiving just 1% of aid, activists say nations ‘cannot continue polluting practices at expense of climate stability’

    Foreign aid for fossil fuel projects quadrupled in a single year, a report has found, rising ​​from $1.2bn in 2021 to $5.4bn in 2022.

    “This shocking increase in aid funding to fossil fuels is a wake-up call,” said Jane Burston, CEO of nonprofit the Clean Air Fund, which conducted the research. “The world cannot continue down this path of propping up polluting practices at the expense of global health and climate stability.”

    Continue reading...

  • As average population falls reach 95% in some regions, experts call for urgent action but insist ‘nature can recover’

    Global wildlife populations have plunged by an average of 73% in 50 years, a new scientific assessment has found, as humans continue to push ecosystems to the brink of collapse.

    Latin America and the Caribbean recorded the steepest average declines in recorded wildlife populations, with a 95% fall, according to the WWF and the Zoological Society of London’s (ZSL) biennial Living Planet report. They were followed by Africa with 76%, and Asia and the Pacific at 60%. Europe and North America recorded comparatively lower falls of 35% and 39% respectively since 1970.

    Continue reading...

  • Badenoch, Cairngorms: Graceful as a folk tale queen, they’re throwing out their arms, feathery green and bearing clusters of bright red berries

    The early October forest is at the turning point, that enchanted time of year when everything is changing form and colour. It havers, slipping backwards and forwards across the threshold between dark and light, the underworld of woodsy rot and the sky-song of geese, the realms of substance and spirit.

    Last night, the stars were fiercely bright and this morning we woke to frost. It still clings to the shadowed hollows of the ground cover and the lacework of spider webs. Higher up, the trees are stirring softly, like a great mystery is coming. The cascading birch boughs are tinged with yellow, the upright aspens a spangling of gold, paper-thin coins trembling against the high blue.

    Continue reading...

  • Prof Pedro Arrojo-Agudo says regulator Ofwat ‘complacent’ about water firms putting their shareholders before public

    The privatised English water system has been singled out for criticism by the UN special rapporteur on the human right to clean water.

    Prof Pedro Arrojo-Agudo said water systems should be managed as a publicly owned service, rather than run by private companies set up to benefit shareholders.

    Continue reading...

  • The Joides Resolution has contributed to our understanding of climate crisis, the origin of life, earthquakes and eruptions. But funding cuts mean it may have sailed its last expedition

    In the early summer of this year, a ship set sail around the Norwegian archipelago of Svalbard. But this wasn’t any ordinary ship. For almost 40 years the Joides Resolutiondrilled into the ocean floor to collect samples and data that helped scientists to study Earth’s history and structure. Expeditions on the vessel have made a vital contribution to our understanding of the climate crisis, the tectonic plates theory, the origin of life on Earth and natural hazards such as earthquakes and eruptions. Yet the two-month voyage around Svalbard was to be its last.

    The National Science Foundation (NSF), the US agency that provided scientists at Texas A&M University with funds for the ship, announced last year it would not give money for the drilling vessel past September 2024. It was a declaration that shocked the global scientific community and meant that Svalbard would be the ship’s final outing.

    The vibration isolated television is attached to the drillpipe and is used to image the seafloor before drilling begins. Photograph: Lisa Crowder/IODP JRSO

    Continue reading...

  • Illness had robbed me of my health, my confidence and my joy. But when my mum brought me something to care for, I regained my sense of purpose

    The life I loved came to an abrupt end when I was diagnosed with severe myalgic encephalomyelitis (ME), also known as chronic fatigue syndrome, in 1997. For years, my world revolved around bedpans, bed baths, wheelchairs and stairlifts. Then an unexpected gift began to revive a sense of joy I thought I had lost for ever.

    I grew up in a gardening-mad household. As a child, I would help my dad tend his prize roses, rake the lawn and carry home the weird-looking leeks and cauliflowers he grew on his allotment. He was my hero and I was never far from his side until he died when I was just 11. From that moment on, gardening lost its appeal: the memories were just too painful. I turned my back on all things green.

    Continue reading...

  • Firefighters are stoic about the risks they face but say climate change has affected every part of the job

    A short drive and a world away from the tourist-thronged old town of Split, past retirees clambering out of cruise ships and stag parties stumbling into beachside bars, Ivan Sanader studied a smouldering hillside that stank of smoke.

    The night before, he had fought a fire that charred the slope and threatened to engulf a roadside restaurant. Now, the commander of a mobile firefighter centre in Croatia was issuing orders to stop it flaring back up.

    Continue reading...

  • This year’s damp high season wasn’t terrible, just typical – but now we judge it against the scorching temperatures of the 2020s

    By general consensus the British summer of 2024 was a bit rubbish – even though the numbers say it was about average. What is behind this clash of perceptions? The Met Office socio-meteorologist Helen Roberts says it is because recent hot summers have changed our expectations.

    “There have been multiple heatwaves in recent years, including the unprecedented extreme heat in 2022 as well as the long, hot lockdown summer of 2020,” says Roberts. She says that two psychological effects, recency bias and the availability heuristic – in which we perceive things through the lens either of recent events or memories that spring readily to mind – “mean we get used to these extremes and then expect more of the same”.

    Continue reading...

  • As Hurricane Milton approaches many cities were largely deserted but some people decided to shelter in place

    Most left when they were told to. But some chose to stay, even though officials warned Hurricane Milton would turn their homes into coffins.

    Along Florida’s Gulf coast, where millions of people were urged to get out of harm’s way, cities were largely deserted on Wednesday afternoon as time ran out to evacuate. Those who remained were advised to shelter in place as best they could. Others who fled spoke of their dread at what, if anything, they would return to once the storm had passed.

    Continue reading...

Novosti: Cybermed.hr

Novosti: Biologija.com

  • Doba u kojem živimo obilježeno je sve bržim promjenama koje se name?‡u morskom okolišu, a gotovo za sve odgovorni su ljudi. Obalna zona Sredozemlja, pa tako i našeg Jadranskoga mora,  mjesto je na kojemu obitava više od polovice ukupnog stanovništva Mediterana te zbog toga ovo usko područje predstavlja i jedan od najugroženijih morskih okoliša.

  • U našem dijelu svijeta, koji zovemo zapadnim i smatramo razvijenim, prije samo 50 godina nisu sve žene imale pravo glasa na izborima, nisu imale jednak pristup obrazovanju, nisu mogle voditi države i nisu imale pristup visokim pozicijama u poslovnom svijetu.

  • Gotovo svi su upoznati s činjenicom kako oceani i mora prekrivaju više od 70 % površine Zemlje. Me?‘utim, nedovoljno je prepoznato kako su oceani, mora i obalna područja esencijalni dio Zemljinih ekosustava te kako o njima ovisi cijelo čovječanstvo, bilo na obali ili u dubokoj unutrašnjosti kontinenata! Zašto?

  • Ovaj cilj održivog razvoja odnosi se na ostvarivanje održive proizvodnje i potrošnje u čemu trenutačno ne uspijevamo jer je ekološki otisak koji ostavljamo i dalje ve?‡i od resursa koje imamo na raspolaganju. Dakle, potrebno je promijeniti načine na koji proizvodimo hranu, smanjiti bacanje hrane, pove?‡ati udjele obnovljive izvore energije u ukupnoj proizvodnji energije, pravilno gospodariti otpadom tijekom čitavog njegovog životnog ciklusa kako bi, me?‘u ostalim što manje utjecali na zaga?‘enje zraka, vode i tla.

  • Razvoj industrije i infrastrukture kao temelja za pove?‡anje životnog standarda za sve ljude, uz okolišno prihvatljiva rješenja te uključivanje novih tehnologija tema je cilja održivog razvoja koji se odnosi na okolišno prihvatljivu industrijalizaciju, kvalitetnu, pouzdanu, održivu i prilagodljivu infrastrukturu, a sve uz primjenu novih tehnologija, istraživanja i inovacija.