




Naturalist says he has been ‘overwhelmed by greetings’ as milestone is marked with event at Royal Albert Hall
David Attenborough said he had been “completely overwhelmed by birthday greetings” for his centenary on Friday and thanked wellwishers “most sincerely”.
The naturalist said he had hoped to celebrate his 100th birthday quietly. Instead, the milestone will be marked with a live event at the Royal Albert Hall broadcast on BBC One, featuring music from his programmes as well as stories and reflections from public figures and leading advocates for the natural world.
In a recorded audio message shared on Thursday night, Attenborough said: “I had rather thought that I would celebrate my 100th birthday quietly, but it seems that many of you have had other ideas.
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Oil firm seeks to reduce stake in carbon capture and storage projects in north-east of England after schemes fail to win over shareholders
BP plans to sell stakes in two flagship carbon capture and storage projects in the north-east of England as the company continues to retreat from the green agenda.
The oil company hopes to reduce its share in the Net Zero Teesside (NZT) project, which aims to develop the UK’s first gas power plant to be fitted with a controversial carbon capture system to remove its emissions.
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In this week’s newsletter: Readers have flooded the crowdfunder of Steve Green after his inspirational story of DIY environmental activism was told
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For many people, owning a yacht is the ultimate dream. But recently I reported on what happens when that dream is abandoned, and one man’s uphill battle to clean up rotting boats left behind in Cornwall, England.
In this week’s newsletter, it’s my pleasure to revisit Cornish boat engineer Steve Green, who says he “nearly fainted” when hundreds of Guardian readers flooded his crowdfunder with donations and notes of thanks after we told his story.
The man who blew up a nuclear power station and disappeared
How car-loving American cities fell so far behind their global peers on public transit
As household bills soar, is it time for a working-class climate agenda?
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Windfall profits could lock in Trump-era political wins for the industry and slow clean-energy transition
The billions in profits big oil is reaping due to the Iran war may stymie the energy transition, experts and advocates fear, incentivizing oil and gas expansion and boosting the sector’s funds for political lobbying.
“Windfall profits from Trump’s war will allow big oil to build a wall of money around its Trump-era political victories,” said Lukas Shankar-Ross, a deputy director at the green group Friends of the Earth.
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This week’s best wildlife photographs from around the world
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Staunton Country Park, Havant: Against my black fleece, this arachnid is startlingly vivid. In the fresh green of the beech canopy, it disappears
The forecast had promised warm spring sunshine – ideal weather for a forest bathing class. Instead, a squally shower arrived without warning, and we ended up hugging tree trunks more out of necessity than mindfulness. In full leaf, the mature beech grove canopy would have kept us dry, but this early in the season, the leaves had only just unfurled, letting the rain through to saturate my jumper. For a while, we listened in silence as the foliage changed its voice, a dry whisper deepening into a steady, percussive patter.
Thankfully, the downpour passed as quickly as it had arrived. Light filtered through the leaves, and we drifted back along the path until the trees opened into a small clearing. The instructor suggested that we sit on a semi-circle of fallen trunks, urging us to feel the texture of the rough-stalked feather moss (Brachythecium rutabulum) cushioning our makeshift benches. Flasks were passed around, the nettle and chamomile tea offering a welcome warmth.
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Bigger cars including electric can cause multiple harms, yet resistance to rise of US-style vehicles has had mixed support
On a brisk winter’s evening in Europe’s automotive heartland, a cyclist who had pushed for safer streets went out on his bike for a final time. Andreas Mandalka had documented dangerous driving and shoddy cycling infrastructure for years, measuring the margins at which cars zipped past him and posting videos of blatant violations. While quick to remind readers that only a small proportion of drivers behaved badly, the 44-year-old blogger in Baden-Württemberg, Germany, had grown frustrated with authorities for failing to act. He felt they viewed him as a nuisance.
As he cycled down a straight stretch of renovated road that runs parallel to a forest path he had flagged for poor quality, lights bright on his bike and helmet firm on his head, he was fatally struck from behind by a car.
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As Trump ramps up pressure by cutting off fuel to the island, Havana’s refuse is rarely collected, forcing residents to burn it in the streets despite the pollution
As thick smoke spread through the narrow streets of Havana, seeping into homes, schools and shops, Carlos Blanco, a chef, opened his bedroom window to see what was going on. “I saw a mist. But it wasn’t mist – it was smoke,” he says, describing the toxic smog emanating from a smouldering mountain of rubbish.
As the US oil blockade on Cuba enters its fourth month, choking off most of the island’s fuel supplies, growing mounds of waste lie on street corners across Havana. Amid fuel scarcity, authorities have opted to ration petrol by reducing waste collection, leaving less than half of Havana’s rubbish trucks operational.
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Powerful radar system is providing new data on city’s subsidence, which experts hope will draw more attention to it
Walking into Mexico City’s sprawling central Zócalo is a dizzying experience. At one end of the plaza, the capital’s cathedral, with its soaring spires, slumps in one direction. An attached church, known as the Metropolitan Sanctuary, tilts in the other. The nearby National Palace also seems off-kilter.
The teetering of many of the capital’s historic buildings is the most visible sign of a phenomenon that has been ongoing for more than a century: Mexico City is sinking at an alarming rate.
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Julie, once a circus elephant, and Kariba, from a Belgian zoo, are to be moved to a former ranch in Portugal
Europe’s first large-scale elephant sanctuary, which is opening to offer a more natural environment for some of the 600 animals still held in captivity across the continent, is to receive its first arrivals.
Julie, Portugal’s last circus elephant, will be moved next month to the animal charity Pangea’s multimillion pound sanctuary in the Alentejo, 200km (124 miles) east of Lisbon, close to the border with Spain.
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Novo istraživanje pokazuje da su isti geni aktivni kod raka gušterače, pretilosti i dijabetesa, što pomaže objasniti zašto se ljudi s metaboličkim bolestima često suočavaju s lošijim ishodima raka i ukazuje na buduće načine predviđanja recidiva i razvoja ciljanijih tretmana.
Amiotrofična lateralna skleroza (ALS) je neurodegenerativna bolest koja uzrokuje progresivni gubitak motornih neurona, što u većini slučajeva dovodi do respiratornog zatajenja unutar tri do pet godina nakon dijagnoze. No, sada je nova studija utvrdila da je stanični selektivni sustav čišćenja proteina: autofagija posredovana šaperonima, značajno smanjen kod pacijenata, što ga čini potencijalnom terapijskom metom za usporavanje napredovanja bolesti.
Rezultati nove studije sugeriraju da su i vrlo niske i vrlo visoke vrijednosti otkucaja srca u mirovanju povezane s povećanim rizikom od moždanog udara. Smatra se, da rezultati ove studije osporavaju pretpostavku da su niži otkucaji srca uvijek znak dobre kardiovaskularne kondicije i da ne nose rizik.
Novo istraživanje pruža dokaze da se sindrom osjetljive kože (SSS) biološki razlikuje od rozaceje, pomažući razjasniti dugogodišnju raspravu u dermatologiji i potencijalno usmjeravajući ciljanije pristupe liječenju.
Desetljećima su se antimikrobni peptidi (AMP) i peptidi koji stvaraju amiloid proučavali u uglavnom odvojenim kontekstima. AMP-ovi su se prvenstveno smatrali urođenim imunološkim efektorima koji pomažu domaćinu u kontroli mikrobne invazije, dok je agregacija amiloida češće bila povezana s poremećajima poput Alzheimerove bolesti (Aβ), Parkinsonove bolesti (α-sinuklein), dijabetesa tipa 2 (hIAPP) i sistemske amiloidoze. Ipak, sve veći broj dokaza dovodi u pitanje ovo jasno odvajanje.
Sepsa, životno opasno stanje uzrokovano disreguliranim odgovorom domaćina na infekciju, ostaje glavni uzrok globalne smrtnosti. Srčana disfunkcija uzrokovana sepsom (SICD), poznata i kao septička kardiomiopatija, značajno pogoršava ishode pacijenata i nedostaju joj ciljane terapije. Iako su upala i metabolički poremećaji poznati kao uzroci, precizni molekularni mehanizmi koji pokreću SICD ostaju slabo shvaćeni, što ometa razvoj učinkovitih tretmana.
Konzumacija jaja povezana je s nižim rizikom od dijagnoze Alzheimerove bolesti za osobe starije od 65 godina, tvrdi nova studija. Naime, konzumacija jednog jajeta dnevno najmanje pet dana u tjednu smanjuje rizik od Alzheimerove bolesti do 27%.
Procjenjuje se da je 7% svih muškaraca pogođeno neplodnošću. Višestruke studije na životinjama pokazale su da izloženost trajnim kemikalijama iz okoliša u ranom životu može negativno utjecati na muško reproduktivno zdravlje, a sada studija na ljudima sugerira isto.
Prema rezultatima nove studije, izgleda da bakterija Akkermansia muciniphila igra značajnu ulogu u regulaciji imuniteta domaćina, održavanju integriteta crijeva i utjecaju na ishode bolesti kod zaraznih i ginekoloških stanja.
Nova tehnika predciljane radioimunoterapije (PRIT) pokazala se sigurnom i učinkovitom u iskorjenjivanju tumora iz predkliničkog modela raka debelog crijeva. Višestupanjski teranostički pristup isporučuje alfa-emitirajuće zračenje izravno tumorima, a istovremeno ograničava izloženost zdravim tkivima.